Normal platelet function
نویسندگان
چکیده
منابع مشابه
Megakaryocytes require thrombospondin-2 for normal platelet formation and function.
Mice that lack the matricellular angiogenesis inhibitor, thrombospondin-2 (TSP2), display a bleeding diathesis, despite normal blood coagulation and the lack of thrombocytopenia. Although platelets do not contain detectable levels of TSP2, TSP2-null platelets are compromised in their ability to aggregate in vivo in response to denudation of the carotid artery endothelium, and in vitro following...
متن کاملRelationships between platelet function tests in normal and uraemic subjects.
IN TESTS OF PLATELET FUNCTION IN NORMAL SUBJECTS, THE FOLLOWING RELATIONSHIPS WERE FOUND: the greater the platelet adhesiveness the less the ability to disaggregate after challenge with adenosine diphosphate (ADP), and the greater the disaggregation after ADP, the longer the clotting time in the test for platelet factor 3 availability. Such correlations were disturbed in uraemic patients.
متن کاملCinnamon inhibits platelet function and improves cardiovascular system
Background: Cinnamon belongs to the Lauraceae family and is one of the most common spices that are used as traditional medicine in the world. The bark and leaf of cinnamon contain essential oils and derivatives including cinnamaldehyde, cinnamic acid and several other compounds such as polyphenols. Moreover, anti-inflammatory and lipid lowering properties of cinnamon has been proven. Objective:...
متن کاملPlatelet serotonin and normal haemostasis.
Serotonin, or 5-hydroxytryptamine (Rapport, 1949), the physiological function of which has not yet been established, is a powerful vasoconstrictor. Carried in the blood by the platelets (Humphrey and Jaques, 1954; Udenfriend and Weissbach, 1954) and released from them as clotting occurs (Zucker and Borrelli, 1955), it has frequently been suggested (Stewart and Zucker, 1913; Reid, 1943; Stefanin...
متن کاملNormal platelet function in platelet concentrates requires non-platelet cells: a comparative in vitro evaluation of leucocyte-rich (type 1a) and leucocyte-poor (type 3b) platelet concentrates
BACKGROUND Therapeutic success of platelet-rich plasma (PRP) may vary based on the composition and preparation method. The objective of this study was to evaluate the cellular components of platelet concentrates produced by a leucocyte-rich (LR-PRP) and a leucocyte-poor PRP systems (LP-PRP). METHODS Parameters evaluated included platelet recovery, platelet concentration, red blood cell (RBC) ...
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ژورنال
عنوان ژورنال: Cancer and Metastasis Reviews
سال: 2017
ISSN: 0167-7659,1573-7233
DOI: 10.1007/s10555-017-9677-x